Description

tert-Butyl 2,7-Diazaspiro[3.5]Nonane-7-Carboxylate Oxalate (Wx100004S4) is a high-purity, protected diazaspiro bicyclic building block essential for modern pharmaceutical research and development. This compound serves as a critical intermediate in the synthesis of complex molecules, offering a rigid, three-dimensional scaffold that is highly valued in medicinal chemistry for exploring novel chemical space. It is primarily utilized by pharmaceutical companies, biotechnology firms, and contract research organizations (CROs) engaged in the discovery of new therapeutic agents, particularly for central nervous system (CNS) and metabolic disease targets.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Scaffold: Used to create structurally diverse compound libraries for high-throughput screening (HTS) and structure-activity relationship (SAR) studies.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a versatile linker or component in the design of bifunctional degrader molecules.
• CNS Drug Discovery: The diazaspiro structure is particularly relevant for designing molecules that target G-protein coupled receptors (GPCRs) and enzymes in the brain.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological pathways and target validation.
• Process Chemistry & Scale-up: Employed in route scouting and optimization for the commercial-scale production of advanced intermediates.

Basic Information

Product Name	tert-Butyl 2,7-Diazaspiro[3.5]Nonane-7-Carboxylate Oxalate (Wx100004S4)
CAS No.	1227381-90-9
Molecular Formula	C15H26N2O5
Molecular Weight	314.38 g/mol
Synonyms	7-Boc-2,7-diazaspiro[3.5]nonane oxalate; 2,7-Diazaspiro[3.5]nonane-7-carboxylic acid, 1,1-dimethylethyl ester, ethanedioate (1:1); tert-Butyl 2,7-diazaspiro[3.5]nonane-7-carboxylate oxalate salt; 7-(tert-Butoxycarbonyl)-2,7-diazaspiro[3.5]nonane oxalic acid salt; Wx100004S4; BOC-2,7-Diazaspiro[3.5]nonane Oxalate; 2,7-Diazaspiro[3.5]nonane-7-carboxylic acid tert-butyl ester oxalate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch of tert-Butyl 2,7-Diazaspiro[3.5]Nonane-7-Carboxylate Oxalate is manufactured and controlled under a strict quality management system. Comprehensive analytical testing, including HPLC, NMR, and MS, is performed to confirm identity, purity, and consistency. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is hygroscopic (moisture-sensitive); ensure the container is sealed under inert atmosphere after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.