Description

1-(Phenylsulfonyl)-2-Methyl-6-Azaindole is a high-purity, advanced pharmaceutical intermediate belonging to the azaindole class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of novel, biologically active molecules, particularly in medicinal chemistry research and development. It is primarily needed by pharmaceutical R&D laboratories, contract research and manufacturing organizations (CROs/CMOs), and agrochemical companies engaged in the discovery of new therapeutic agents and crop protection products.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Synthesis: Serves as a precursor in the development of novel pesticides and herbicides with specific modes of action.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target validation.
• Custom Synthesis & Scale-Up: Supplied for custom manufacturing projects, from milligram-scale research to multi-kilogram pilot plant production.
• Academic Research: Employed in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	1-(Phenylsulfonyl)-2-Methyl-6-Azaindole
CAS No.	1227270-25-8
Molecular Formula	C15H12N2O2S
Molecular Weight	284.33 g/mol
Synonyms	2-Methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 2-methyl-1-(phenylsulfonyl)-; 2-Methyl-1-(benzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine; 2-Methyl-1-tosyl-6-azaindole (common misnomer); 1-(Phenylsulfonyl)-2-methyl-1H-pyrrolo[2,3-b]pyridine; 2-Methyl-6-azaindole-1-sulfonylbenzene; 1-Benzenesulfonyl-2-methyl-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 1-(Phenylsulfonyl)-2-Methyl-6-Azaindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.