Description

4-Chloro-1-(Phenylsulfonyl)-1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound serves as a critical building block in modern medicinal chemistry, enabling the synthesis of novel therapeutic agents. It is primarily sought after by R&D laboratories and production facilities in the pharmaceutical and biotechnology sectors for the development of targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and antiviral research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• Chemical Synthesis Building Block: Employed in the construction of complex heterocyclic frameworks due to its reactive chloro and carboxylic acid functional groups.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural component in the development of potential new APIs.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs engaged in custom synthesis and process development for clients.
• Academic Research: Utilized in university and institutional labs for exploratory research in organic synthesis and drug discovery.

Basic Information

Product Name	4-Chloro-1-(Phenylsulfonyl)-1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid
CAS No.	1227268-65-6
Molecular Formula	C16H11ClN2O4S
Molecular Weight	362.79 g/mol
Synonyms	4-Chloro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid; 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 4-chloro-1-(phenylsulfonyl)-; 4-Chloro-1-(benzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid; 1227268-65-6; 4-Chloro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid; 4-Chloro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid (CAS 1227268-65-6)
EINECS	Contact for details

Quality Control

Our 4-Chloro-1-(Phenylsulfonyl)-1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry for identity confirmation. Certificates of Analysis (COA) are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.