Description

1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is a high-purity heterocyclic building block of significant importance in modern pharmaceutical research and development. This compound serves as a critical synthetic intermediate for constructing novel drug candidates, particularly in kinase inhibitor programs. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of small molecule kinase inhibitors and other targeted therapeutics.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Process Chemistry Development: Serves as a starting material for scaling up synthetic routes to clinical trial and commercial API batches.
• Chemical Biology Probes: Utilized in the development of chemical probes for studying biological pathways and target validation.
• Custom Synthesis: Employed by fine chemical manufacturers for producing custom-designed heterocyclic compounds for clients.
• Academic Research: Used in university and institutional labs for developing new synthetic methodologies and exploring novel chemical space.

Basic Information

Product Name	1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid
CAS No.	1227267-26-6
Molecular Formula	C7H5N3O2
Molecular Weight	163.14 g/mol
Synonyms	1H-Pyrazolo[3,4-b]pyridine-4-carboxylic acid; 4-Pyrazolo[3,4-b]pyridinecarboxylic acid; 1H-Pyrazolo[3,4-b]pyridine-4-carboxylic acid; 4-Carboxy-1H-pyrazolo[3,4-b]pyridine; Pyrazolo[3,4-b]pyridine-4-carboxylic acid; 1227267-26-6; 4-(1H-Pyrazolo[3,4-b]pyridin-4-yl)carboxylic acid
EINECS	Contact for details

Quality Control

Our 1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.