Description

Cyclohexanecarboxylic Acid, 4-(1-Methylethoxy)-, Ethyl Ester, trans- is a specialized organic ester compound characterized by its trans-configured cyclohexane ring substituted with an isopropoxy group. This specific stereochemistry and functional group arrangement make it a valuable chiral intermediate and building block in advanced synthetic chemistry. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of complex, high-value target molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting the central nervous system or possessing complex stereocenters.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where specific stereochemistry is crucial for biological activity and environmental profile.
• Liquid Crystal & Advanced Material Precursor: Serves as a building block for organic electronic materials and liquid crystal compounds due to its rigid, substituted cyclohexane core.
• Flavor & Fragrance Chemistry: Potential intermediate for synthesizing specific ester-based aroma chemicals, leveraging its unique structural motif.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development in asymmetric synthesis and catalysis studies.
• Fine Chemical Manufacturing: A versatile intermediate for custom synthesis projects requiring high-purity, stereodefined carboxylic acid derivatives.

Basic Information

Product Name	Cyclohexanecarboxylic Acid, 4-(1-Methylethoxy)-, Ethyl Ester, trans-
CAS No.	1227187-59-8
Molecular Formula	C12H22O3
Molecular Weight	214.30 g/mol
Synonyms	trans-4-Isopropoxycyclohexanecarboxylic Acid Ethyl Ester; Ethyl trans-4-Isopropoxycyclohexanecarboxylate; trans-Ethyl 4-Isopropoxycyclohexanecarboxylate; 4-(1-Methylethoxy)cyclohexanecarboxylic Acid Ethyl Ester, trans-; (1r,4r)-Ethyl 4-(Isopropoxy)cyclohexanecarboxylate; (trans)-Ethyl 4-(Isopropyloxy)cyclohexanecarboxylate; Ethyl (trans)-4-(Isopropoxy)cyclohexanecarboxylate
EINECS	Contact for details

Quality Control

Our Cyclohexanecarboxylic Acid, 4-(1-Methylethoxy)-, Ethyl Ester, trans- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support custom synthesis and can tailor specifications, including enantiomeric excess (ee), to meet specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (trans-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.