Description

1-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-5,6-Dihydropyridin-1(2H)-Yl)Ethanone is a high-value, protected boronic ester derivative that serves as a critical synthetic intermediate. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds in advanced organic synthesis. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is used to build novel molecular scaffolds for drug discovery and active ingredient development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for small molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides through structure-activity relationship (SAR) studies.
• Material Science: Potential monomer or precursor for creating functional polymers and advanced organic electronic materials.
• Chemical Biology: Serves as a probe or linker in bioconjugation chemistry and the development of biochemical tools.
• Academic & Contract Research: Enables methodological development and the synthesis of complex, boronate-containing molecules in research laboratories.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of fine chemicals.

Basic Information

Product Name	1-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-5,6-Dihydropyridin-1(2H)-Yl)Ethanone
CAS No.	1227068-67-8
Molecular Formula	C13H22BNO3
Molecular Weight	251.13 g/mol
Synonyms	1-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,6-tetrahydropyridin-1-yl]ethanone; 1-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-2H-pyridin-1-yl]ethanone; 1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5,6-dihydro-2H-pyridin-1-yl)ethanone; 2-(1-Acetyl-1,2,3,6-tetrahydropyridin-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Acetyl MIDA Boronate Derivative (related class); Pinacol Boronate Ester Intermediate
EINECS	Contact for details

Quality Control

Our 1-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-5,6-Dihydropyridin-1(2H)-Yl)Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with ISO, GMP, and other relevant regulatory frameworks for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption and decomposition. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.