Description

2-Amino-4-Chloro-5-Fluoro-1-Methyl-6-Oxo-1,6-Dihydropyridine-3-Carbonitrile is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its complex molecular architecture, featuring amino, chloro, fluoro, and cyano substituents, makes it a versatile and critical intermediate for constructing sophisticated pharmacophores. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors who require reliable, high-quality raw materials for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Research: Serves as a building block for creating new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Chemical Synthesis: Used in academic and industrial research laboratories for constructing complex pyridine and dihydropyridine derivatives for material science and catalysis studies.
• Active Pharmaceutical Ingredient (API) Development: Employed in the research-scale synthesis of potential API cores, leveraging its halogen and nitrile functionalities for further derivatization.

Basic Information

Product Name	2-Amino-4-Chloro-5-Fluoro-1-Methyl-6-Oxo-1,6-Dihydropyridine-3-Carbonitrile
CAS No.	1227053-98-6
Molecular Formula	C7H5ClFN3O
Molecular Weight	201.58 g/mol
Synonyms	2-Amino-4-chloro-5-fluoro-1-methyl-6-oxo-1,6-dihydropyridine-3-carbonitrile; 4-Chloro-5-fluoro-1-methyl-6-oxo-2-amino-1,6-dihydropyridine-3-carbonitrile; 1,6-Dihydro-2-amino-4-chloro-5-fluoro-1-methyl-6-oxo-3-pyridinecarbonitrile; 3-Cyano-2-amino-4-chloro-5-fluoro-1-methyl-6(1H)-pyridinone
EINECS	Contact for details

Quality Control

Our 2-Amino-4-Chloro-5-Fluoro-1-Methyl-6-Oxo-1,6-Dihydropyridine-3-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP and ISO standards ensures a reliable supply of this high-value intermediate for your critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.