Description

2-Chloro-3-Iodopyridin-4-Ol is a halogenated pyridine derivative serving as a versatile and high-value synthetic intermediate in advanced organic chemistry. Its unique substitution pattern makes it a critical building block for constructing complex molecular architectures, particularly in pharmaceutical discovery and agrochemical development. This compound is essential for researchers and process chemists in the life sciences and fine chemical sectors seeking to introduce specific halogen functionalities into heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for transition metal catalysis and cross-coupling reactions.
• Material Science Research: Intermediate for creating functionalized organic molecules used in organic electronics and advanced polymers.
• Chemical Biology Probes: Serves as a starting material for synthesizing molecular probes and tags for studying biological systems.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and development candidates.

Basic Information

Product Name	2-Chloro-3-Iodopyridin-4-Ol
CAS No.	1226879-01-1
Molecular Formula	C5H3ClINO
Molecular Weight	255.44 g/mol
Synonyms	4-Hydroxy-2-chloro-3-iodopyridine; 2-Chloro-3-iodopyridin-4-ol; 3-Iodo-2-chloropyridin-4-ol; 2-Chloro-3-iodo-4-hydroxypyridine; 2-Chloro-3-iodo-4-pyridinol; 4-Pyridinol, 2-chloro-3-iodo-; 2-Chloro-3-iodo-4(1H)-pyridinone (tautomer)
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Iodopyridin-4-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); handle and store under inert atmosphere if prolonged storage is required.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.