Description

6-Fluorothiazolo[4,5-B]Pyridine-2-Thiol is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmaceuticals and agrochemicals, where its unique fused thiazolopyridine core introduces specific bioactivity and physicochemical properties. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and material science industries for creating new active ingredients and functional molecules. CAS No. 1226808-69-0.

Application

This specialized intermediate is utilized in sophisticated chemical synthesis across several high-tech sectors:

• Pharmaceutical Intermediate: Serves as a critical scaffold in the research and development of new drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging the biological activity of the thiazole and fluorinated pyridine motifs.
• Material Science Research: Acts as a building block for developing advanced organic electronic materials, such as ligands for catalysts or components in organic semiconductors.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring complex, fluorinated heterocyclic architectures.

Basic Information

Product Name	6-Fluorothiazolo[4,5-B]Pyridine-2-Thiol
CAS No.	1226808-69-0
Molecular Formula	C6H3FN2S2
Molecular Weight	186.23 g/mol
Synonyms	6-Fluoro[1,3]thiazolo[4,5-b]pyridine-2-thiol; 2-Thiol-6-fluorothiazolo[4,5-b]pyridine; 6-Fluoro-2-mercaptothiazolo[4,5-b]pyridine; 6-Fluoro-2-thioxo-2,3-dihydrothiazolo[4,5-b]pyridine; 1226808-69-0; Thiazolo[4,5-b]pyridine-2-thiol, 6-fluoro-
EINECS	Contact for details

Quality Control

Our production of 6-Fluorothiazolo[4,5-B]Pyridine-2-Thiol adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for your critical synthesis work. All materials undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We operate under a quality management system and can support development projects requiring compliance with cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening the primary container to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.