Description

2-Chloro-4-(1-Hydroxy-Cycloheptyl)-Nicotinonitrile is a high-value, functionalized pyridine derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring a chloro-substituted pyridine core fused with a hydroxy-cycloheptyl moiety, makes it an essential building block for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive pyridine scaffold.
• Ligand and Catalyst Synthesis: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Building block for advanced polymers and organic electronic materials requiring specific nitrogen-containing heterocycles.
• Chemical Biology Probes: Utilized in the design of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	2-Chloro-4-(1-Hydroxy-Cycloheptyl)-Nicotinonitrile
CAS No.	1226772-18-4
Molecular Formula	C13H15ClN2O
Molecular Weight	250.72 g/mol
Synonyms	2-Chloro-4-(1-hydroxycycloheptyl)nicotinonitrile; 2-Chloro-4-(1-hydroxycycloheptyl)-3-cyanopyridine; Nicotinonitrile, 2-chloro-4-(1-hydroxycycloheptyl)-; 4-(1-Hydroxycycloheptyl)-2-chloronicotinonitrile; 2-Chloro-4-(hydroxycycloheptyl)pyridine-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(1-Hydroxy-Cycloheptyl)-Nicotinonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.