Description

5-(4-(Trifluoromethyl)Phenyl)Pyridin-3-Amine CAS NO 1225829-49-1 is a high-purity, advanced pharmaceutical intermediate featuring a trifluoromethylphenyl-pyridine core structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing next-generation products.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the research and synthesis of potential drug candidates, especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in developing advanced active ingredients for crop protection products, leveraging the biological activity of the trifluoromethyl and pyridine motifs.
• Material Science: Acts as a monomer or functional additive in the creation of specialty polymers and advanced organic electronic materials.
• Chemical Synthesis: Employed as a versatile building block in organic chemistry for constructing complex heterocyclic compounds in academic and industrial R&D.
• Ligand Synthesis: Utilized in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	5-(4-(Trifluoromethyl)Phenyl)Pyridin-3-Amine
CAS No.	1225829-49-1
Molecular Formula	C12H9F3N2
Molecular Weight	238.21 g/mol
Synonyms	3-Amino-5-[4-(trifluoromethyl)phenyl]pyridine; 5-[4-(Trifluoromethyl)phenyl]pyridin-3-amine; 5-(4-Trifluoromethylphenyl)-3-pyridinamine; 3-Pyridinamine, 5-[4-(trifluoromethyl)phenyl]-; 1225829-49-1
EINECS	Contact for details

Quality Control

Our 5-(4-(Trifluoromethyl)Phenyl)Pyridin-3-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.