Description

1-(2-Methoxyphenyl)-5-Methyl-1H-Pyrazole-3-Carboxylic Acid is a high-purity, functionalized pyrazole derivative serving as a critical building block in advanced organic synthesis. This compound matters because it provides a versatile scaffold for constructing complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for lead optimization and scale-up activities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or possessing anti-inflammatory activity.
• Agrochemical Research: Used as a core structure for developing new herbicides, fungicides, or insecticides with improved efficacy and selectivity.
• Ligand Synthesis: Serves as a starting material for creating complex chelating ligands used in catalysis or metal-organic frameworks (MOFs).
• Material Science: Building block for specialty polymers or organic electronic materials due to its aromatic and heterocyclic structure.
• Chemical Biology Probes: Utilized in medicinal chemistry to create tool compounds for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring high-purity intermediates.

Basic Information

Product Name	1-(2-Methoxyphenyl)-5-Methyl-1H-Pyrazole-3-Carboxylic Acid
CAS No.	1225539-41-2
Molecular Formula	C12H12N2O3
Molecular Weight	232.24 g/mol
Synonyms	5-Methyl-1-(2-methoxyphenyl)-1H-pyrazole-3-carboxylic acid; 1H-Pyrazole-3-carboxylic acid, 1-(2-methoxyphenyl)-5-methyl-; 1-(2-Methoxyphenyl)-5-methylpyrazole-3-carboxylic acid; 2-Methoxyphenyl 5-methyl-1H-pyrazole-3-carboxylate (tautomer); o-Methoxyphenyl 5-methylpyrazole-3-carboxylic acid; 5-Methyl-1-(o-methoxyphenyl)pyrazole-3-carboxylic acid; Pyrazole-3-carboxylic acid derivative, CAS 1225539-41-2
EINECS	Contact for details

Quality Control

Our 1-(2-Methoxyphenyl)-5-Methyl-1H-Pyrazole-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its carboxylic acid functionality, keep away from strong bases and oxidizing agents. For long-term storage, consider inert atmosphere conditions to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.