Description

2-(3,5-Difluorophenyl)Nicotinic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its specific difluorophenyl-substituted nicotinic acid structure. This compound is of significant value for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular modification. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging the biological activity of the difluorophenyl moiety.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands in catalysis and material science.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic routes.
• Academic Research: Used in university and institutional labs for methodological development and novel heterocyclic chemistry studies.

Basic Information

Product Name	2-(3,5-Difluorophenyl)Nicotinic Acid
CAS No.	1225477-61-1
Molecular Formula	C12H7F2NO2
Molecular Weight	235.19 g/mol
Synonyms	2-(3,5-Difluorophenyl)pyridine-3-carboxylic acid; Nicotinic acid, 2-(3,5-difluorophenyl)-; 3-Pyridinecarboxylic acid, 2-(3,5-difluorophenyl)-; 2-(3,5-Difluorophenyl)-3-pyridinecarboxylic acid; 2-(3,5-Difluorophenyl)nicotinate; 1225477-61-1
EINECS	Contact for details

Quality Control

Our 2-(3,5-Difluorophenyl)Nicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.