Description

3-Aza-Spiro[5.5]Undecan-9-One Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic amine structure. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of central nervous system (CNS) therapeutics and other complex small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in CNS and neurological disorder research.
• Medicinal Chemistry R&D: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Organic Synthesis: Serves as a versatile precursor for constructing complex spirocyclic and heterocyclic frameworks in academic and industrial laboratories.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for cGMP production of clinical trial materials.
• Chemical Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	3-Aza-Spiro[5.5]Undecan-9-One Hydrochloride
CAS No.	1225437-09-1
Molecular Formula	C10H18ClNO
Molecular Weight	203.71 g/mol
Synonyms	9-Oxo-3-azaspiro[5.5]undecane hydrochloride; 3-Azaspiro[5.5]undecan-9-one, hydrochloride; 3-Aza-spiro[5.5]undecane-9-one HCl; 9-Keto-3-azaspiro[5.5]undecane hydrochloride; 1225437-09-1; 3-Aza-Spiro[5.5]Undecan-9-One HCl; 3-Azaspiro[5.5]undecan-9-one HCl salt
EINECS	Contact for details

Quality Control

Our 3-Aza-Spiro[5.5]Undecan-9-One Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support development and commercial projects with material that meets stringent internal specifications, suitable for use in cGMP environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.