Description

Benzenamine, 2,5-Difluoro-4-[[2-(1-Methyl-1H-Pyrazol-4-Yl)-4-Pyridinyl]Oxy]- is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound matters because it serves as a critical building block in modern medicinal chemistry, enabling the development of targeted therapies. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the discovery and production of innovative small-molecule drugs, particularly in oncology and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, especially kinase inhibitors.
• Research & Development (R&D): Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Synthesis: Incorporated into the final molecular structure of target APIs for clinical development.
• Contract Manufacturing (CMO/CDMO): Supplied to contract research and manufacturing organizations for scale-up and cGMP production.
• Biochemical Research: Employed as a tool compound in biochemical assays to study specific biological pathways and target interactions.

Basic Information

Item	Details
Product Name	Benzenamine, 2,5-Difluoro-4-[[2-(1-Methyl-1H-Pyrazol-4-Yl)-4-Pyridinyl]Oxy]-
CAS No.	1225278-35-2
Molecular Formula	C15H12F2N4O
Molecular Weight	302.28 g/mol
Synonyms	2,5-Difluoro-4-((2-(1-methyl-1H-pyrazol-4-yl)pyridin-4-yl)oxy)aniline; 4-[[2-(1-Methyl-1H-pyrazol-4-yl)-4-pyridinyl]oxy]-2,5-difluoro-Benzenamine; 2,5-Difluoro-4-((2-(1-methyl-1H-pyrazol-4-yl)pyridin-4-yl)oxy)phenylamine; 1225278-35-2; Aniline, 2,5-difluoro-4-[[2-(1-methyl-1H-pyrazol-4-yl)-4-pyridinyl]oxy]-
EINECS	Contact for details

Quality Control

Our Benzenamine, 2,5-Difluoro-4-[[2-(1-Methyl-1H-Pyrazol-4-Yl)-4-Pyridinyl]Oxy]- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.