Description

tert-Butyl 3-(3-(Dimethylamino)acryloyl)pyrrolidine-1-carboxylate is a high-value, advanced pharmaceutical intermediate featuring a versatile pyrrolidine scaffold. This compound is critical for the synthesis of complex molecules, particularly in medicinal chemistry, due to its functional groups that enable further derivatization. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• API Development: Serves as a precursor in the multi-step synthesis of complex, high-potency active pharmaceutical ingredients.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic projects.

Basic Information

Product Name	tert-Butyl 3-(3-(Dimethylamino)acryloyl)pyrrolidine-1-carboxylate
CAS No.	1225218-91-6
Molecular Formula	C14H24N2O3
Molecular Weight	268.35 g/mol
Synonyms	1-Boc-3-(3-(dimethylamino)acryloyl)pyrrolidine; 1-(tert-Butoxycarbonyl)-3-[3-(dimethylamino)-1-oxo-2-propen-1-yl]pyrrolidine; tert-Butyl 3-(3-(dimethylamino)-1-oxo-2-propenyl)-1-pyrrolidinecarboxylate; 3-(3-(Dimethylamino)acryloyl)pyrrolidine-1-carboxylic acid tert-butyl ester; 1225218-91-6; Boc-3-(3-(dimethylamino)acryloyl)pyrrolidine
EINECS	Contact for details

Quality Control

Our production of tert-Butyl 3-(3-(Dimethylamino)acryloyl)pyrrolidine-1-carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is characterized and released using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.