Description

6-Bromo-3-Hydroxyisobenzofuran-1(3H)-One is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides, leveraging its brominated isobenzofuranone core.
• Material Science Research: Serves as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and cellular processes.
• Ligand and Catalyst Development: Utilized as a scaffold for creating novel ligands and organocatalysts used in asymmetric synthesis.
• Academic & Contract Research: A valuable reagent for methodological studies and the exploration of new chemical reactions in academic and industrial R&D settings.

Basic Information

Product Name	6-Bromo-3-Hydroxyisobenzofuran-1(3H)-One
CAS No.	1225206-60-9
Molecular Formula	C8H5BrO3
Molecular Weight	229.03 g/mol
Synonyms	6-Bromo-3-hydroxy-1(3H)-isobenzofuranone; 6-Bromo-3-hydroxyphthalide; 3-Hydroxy-6-bromophthalide; 6-Bromo-3-hydroxylisobenzofuran-1-one; 6-Bromophthalide-3-ol; 1225206-60-9; 6-Bromo-3-hydroxy-1,3-dihydroisobenzofuran-1-one
EINECS	Contact for details

Quality Control

Our 6-Bromo-3-Hydroxyisobenzofuran-1(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports applications requiring high standards, such as pharmaceutical R&D and material science.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and away from direct light sources to maintain stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.