Description

6-(Piperazin-1-yl)nicotinaldehyde is a high-purity, versatile heterocyclic building block and key synthetic intermediate. This compound is of significant commercial importance due to its bifunctional structure, featuring both a reactive aldehyde group and a piperazine moiety, which facilitates its use in complex molecular construction. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Chemical Research & Development: Serves as a versatile building block for constructing complex molecular libraries in medicinal chemistry and material science.
• Ligand and Catalyst Development: The piperazine nitrogen atoms can act as coordination sites for metal complexes used in catalysis.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals and advanced materials.

Basic Information

Product Name	6-(Piperazin-1-yl)nicotinaldehyde
CAS No.	1225065-40-6
Molecular Formula	C10H13N3O
Molecular Weight	191.23 g/mol
Synonyms	6-(Piperazin-1-yl)pyridine-3-carbaldehyde; 3-Formyl-6-(1-piperazinyl)pyridine; 6-Piperazin-1-yl-nicotinaldehyde; 6-(1-Piperazinyl)-3-pyridinecarboxaldehyde; 3-Pyridinecarboxaldehyde, 6-(1-piperazinyl)-; Nicotinaldehyde, 6-(piperazin-1-yl)-
EINECS	Contact for details

Quality Control

Our 6-(Piperazin-1-yl)nicotinaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.