Description

Methyl 5'-Methyl-5-(1,3-Thiazol-2-Yl)-2,3'-Bipyridine-4-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. Pharmaceutical R&D teams and fine chemical manufacturers need this precise intermediate to develop next-generation drug candidates targeting specific biological pathways.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of complex drug molecules, especially in oncology and antiviral research.
• Active Pharmaceutical Ingredient (API) Development: Used as a core scaffold for developing new APIs with targeted biological activity.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying enzyme function and cellular signaling pathways.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Used in university and institutional labs for pioneering research in heterocyclic and medicinal chemistry.

Basic Information

Product Name	Methyl 5'-Methyl-5-(1,3-Thiazol-2-Yl)-2,3'-Bipyridine-4-Carboxylate
CAS No.	1224846-10-9
Molecular Formula	C₁₈H₁₅N₃O₂S
Molecular Weight	337.40 g/mol
Synonyms	Methyl 5'-methyl-5-(thiazol-2-yl)-2,3'-bipyridine-4-carboxylate; 4-Pyridinecarboxylic acid, 5'--methyl-5-(2-thiazolyl)-2,3'-bipyridin-, methyl ester; 2,3'-Bipyridine, 5'--methyl-5-(2-thiazolyl)-, 4-carboxylic acid methyl ester; Methyl 5'--methyl-5-(1,3-thiazol-2-yl)-2,3'-bipyridine-4-carboxylate; CAS 1224846-10-9
EINECS	Contact for details

Quality Control

Our production of Methyl 5'-Methyl-5-(1,3-Thiazol-2-Yl)-2,3'-Bipyridine-4-Carboxylate adheres to stringent quality management protocols, ensuring batch-to-batch consistency suitable for pharmaceutical R&D. All material is characterized and released against comprehensive specifications, including identity confirmation by spectroscopic methods and purity assessment by HPLC. A Certificate of Analysis (COA) detailing purity, impurities, and analytical results is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.