Description

2H-1-Benzopyran-2-One, 4-(4-Fluorophenyl)-3,4-Dihydro- is a high-purity fluorinated coumarin derivative, a key structural motif in advanced organic synthesis. This compound is valued for its role as a versatile synthetic intermediate and a potential pharmacophore in the development of novel active ingredients. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating new molecules with targeted biological or functional properties.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel drug candidates, particularly those targeting neurological or metabolic pathways.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the bioactivity of the coumarin scaffold.
• Organic Light-Emitting Diode (OLED) Materials: Acts as a precursor for fluorinated organic semiconductors and emissive layer materials.
• Fluorescent Probe Synthesis: Utilized to create advanced fluorescent dyes and sensors for biochemical and diagnostic applications.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and exploratory chemistry projects.
• Fine Chemical Synthesis: A key intermediate for producing complex, high-value specialty chemicals with specific fluorinated architectures.

Basic Information

Product Name	2H-1-Benzopyran-2-One, 4-(4-Fluorophenyl)-3,4-Dihydro-
CAS No.	1224738-67-3
Molecular Formula	C₁₅H₁₁FO₂
Molecular Weight	242.25 g/mol
Synonyms	4-(4-Fluorophenyl)-3,4-dihydro-2H-chromen-2-one; 4-(4-Fluorophenyl)-3,4-dihydrocoumarin; 4-(p-Fluorophenyl)-3,4-dihydro-2H-1-benzopyran-2-one; 4-(4-Fluorophenyl)dihydrocoumarin; Fluorophenyl Dihydrocoumarin; Dihydrocoumarin, 4-(4-fluorophenyl)-; 1224738-67-3
EINECS	Contact for details

Quality Control

Our 2H-1-Benzopyran-2-One, 4-(4-Fluorophenyl)-3,4-Dihydro- is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP and ISO compliant documentation for advanced research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.