Description

2-Chloro-4-Ethynyl-Benzoic Acid Methyl Ester (Wx686208) is a specialized aromatic ester building block featuring both chloro and ethynyl functional groups. This unique bifunctional structure makes it a valuable intermediate for synthesizing complex molecules in advanced research and development. It is primarily utilized by pharmaceutical and agrochemical R&D teams for constructing novel active ingredients and functional materials. Our supply ensures high purity and batch-to-batch consistency critical for sensitive synthetic pathways.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors or other small-molecule therapeutics.
• Agrochemical Research: Serves as a versatile building block for creating novel herbicides, fungicides, or plant growth regulators with tailored properties.
• Material Science Precursor: Used in the synthesis of advanced polymers, liquid crystals, or organic electronic materials due to its reactive ethynyl group for cross-coupling or polymerization reactions.
• Chemical Synthesis: Employed in organic synthesis as a versatile intermediate for Sonogashira coupling, click chemistry, and other palladium-catalyzed transformations.
• Academic & Industrial R&D: Essential for exploratory chemistry in university laboratories and corporate R&D centers focusing on heterocyclic and aromatic compound libraries.

Basic Information

Product Name	2-Chloro-4-Ethynyl-Benzoic Acid Methyl Ester (Wx686208)
CAS No.	1224640-19-0
Molecular Formula	C10H7ClO2
Molecular Weight	194.61 g/mol
Synonyms	Methyl 2-Chloro-4-ethynylbenzoate; 2-Chloro-4-ethynylbenzoic Acid Methyl Ester; Benzoic acid, 2-chloro-4-ethynyl-, methyl ester; WX-686208; Wx686208
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Ethynyl-Benzoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and GC for residual solvent analysis, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.