Description

5-Bromo-n-Methoxy-N,3-Dimethylpicolinamide is a high-purity, advanced pharmaceutical intermediate with a distinct brominated picolinamide structure. This compound matters for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific bromine and methoxy functionalities into novel molecular scaffolds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Agrochemical Synthesis: Serves as an intermediate in the development of new herbicides and fungicides with enhanced activity.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for specialized, high-value chemical products.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	5-Bromo-n-Methoxy-N,3-Dimethylpicolinamide
CAS No.	1224604-14-1
Molecular Formula	C10H13BrN2O2
Molecular Weight	273.13 g/mol
Synonyms	5-Bromo-N-methoxy-N,3-dimethylpyridine-2-carboxamide; 5-Bromo-2-(methoxy(methyl)carbamoyl)-3-methylpyridine; 5-Bromo-3-methyl-N-methoxy-N-methylpicolinamide; 2-Pyridinecarboxamide, 5-bromo-N-methoxy-N,3-dimethyl-; 5-Bromo-N,3-dimethyl-N-methoxypicolinamide; 5-Bromo-3-methyl-picolinic acid methoxy-methyl-amide
EINECS	Contact for details

Quality Control

Our 5-Bromo-n-Methoxy-N,3-Dimethylpicolinamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.