Description

1,4,8-Triazaspiro[4.5]Decan-2-One, 8-Methyl-1-(Phenylmethyl)- is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic triaza structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of new drug candidates, especially those targeting the central nervous system (CNS) and other specialized therapeutic areas.
• Organic Synthesis Building Block: Utilized in medicinal chemistry for constructing complex heterocyclic frameworks due to its spirocyclic and nitrogen-rich core.
• Research & Development (R&D): Serves as a valuable reagent in academic and industrial R&D labs for exploring new chemical entities and reaction pathways.
• API Process Development: Employed in the scale-up and optimization of synthetic routes for potential Active Pharmaceutical Ingredients during pre-clinical and clinical stages.
• Ligand and Catalyst Research: Its structure may be explored in the design of novel ligands for catalysis or in materials science applications.

Basic Information

Product Name	1,4,8-Triazaspiro[4.5]Decan-2-One, 8-Methyl-1-(Phenylmethyl)-
CAS No.	1224591-33-6
Molecular Formula	C15H21N3O
Molecular Weight	259.35 g/mol
Synonyms	8-Methyl-1-(phenylmethyl)-1,4,8-triazaspiro[4.5]decan-2-one; 8-Methyl-1-benzyl-1,4,8-triazaspiro[4.5]decan-2-one; 1-Benzyl-8-methyl-1,4,8-triazaspiro[4.5]decan-2-one; 1,4,8-Triazaspiro[4.5]decan-2-one, 8-methyl-1-(phenylmethyl)-; Spirocyclic Triaza Ketone Intermediate; CAS 1224591-33-6
EINECS	Contact for details

Quality Control

Our production of 1,4,8-Triazaspiro[4.5]Decan-2-One, 8-Methyl-1-(Phenylmethyl)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials are subjected to rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. Certificates of Analysis (COA) are provided with each shipment, detailing all relevant specifications. We operate under a quality system designed to meet the standards required for pharmaceutical R&D and cGMP starting material applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.