Description

1-Azaspiro[3.3]heptane, 1-(phenylmethyl)- is a high-value, nitrogen-containing spirocyclic building block of significant interest in modern organic synthesis. Its unique bridged bicyclic structure, featuring a spiro-fused azetidine and cyclobutane, makes it a privileged scaffold for constructing novel molecular architectures with potential biological activity. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides, leveraging its spirocyclic framework for enhanced bioactivity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probe Synthesis: Employed to construct molecular probes for studying enzyme function and protein-protein interactions within biological systems.
• Material Science Precursor: Potential use in the synthesis of advanced polymers and functional materials with specific thermal or optical properties.

Basic Information

Product Name	1-Azaspiro[3.3]heptane, 1-(phenylmethyl)-
CAS No.	1223573-40-7
Molecular Formula	C12H15N
Molecular Weight	173.26 g/mol
Synonyms	1-Benzyl-1-azaspiro[3.3]heptane; 1-Benzylazaspiro[3.3]heptane; N-Benzyl-1-azaspiro[3.3]heptane; 1-Azaspiro[3.3]heptane, 1-benzyl-; 1-(Phenylmethyl)-1-azaspiro[3.3]heptane; N-Benzylazaspiro[3.3]heptane; 1-Benzyl-1-aza-spiro[3.3]heptane
EINECS	Contact for details

Quality Control

Our 1-Azaspiro[3.3]heptane, 1-(phenylmethyl)- is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.