Description

5-Bromo-2-Ethyl-1H-Pyrrolo[2,3-B]Pyridine is a high-value brominated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in the development of novel pharmaceuticals and agrochemicals. It is primarily needed by research institutions and industrial R&D departments focused on medicinal chemistry, where it serves as a key precursor for kinase inhibitors and other biologically active molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of targeted small-molecule drugs, particularly protein kinase inhibitors for oncology and inflammatory diseases.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a precursor for organic electronic materials, such as ligands for OLEDs or conductive polymers, due to its fused pyrrolopyridine structure.
• Chemical Biology: Employed in the design and synthesis of chemical probes and tool compounds for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex APIs for clients.

Basic Information

Product Name	5-Bromo-2-Ethyl-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	1222533-88-1
Molecular Formula	C9H9BrN2
Molecular Weight	225.09 g/mol
Synonyms	5-Bromo-2-ethyl-1H-pyrrolo[2,3-b]pyridine; 2-Ethyl-5-bromo-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 5-bromo-2-ethyl-; 5-Bromo-2-ethyl-7-azaindole; 5-Bromo-2-ethyl-1H-7-azaindole; 5-Bromo-2-ethyl-7-aza-indole
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Ethyl-1H-Pyrrolo[2,3-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.