Description

5-Bromo-1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate and heterocyclic building block of significant commercial interest. This compound is valued for its unique fused-ring structure, which serves as a critical scaffold in modern medicinal chemistry for the development of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of active pharmaceutical ingredients (APIs) and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of kinase inhibitors and other targeted small-molecule drugs.
• Drug Discovery & Medicinal Chemistry: Used as a versatile scaffold for constructing compound libraries and exploring structure-activity relationships (SAR).
• Agrochemical Research: Serves as a precursor in the development of new crop protection agents and pesticides.
• Material Science: Potential use in the synthesis of organic electronic materials and ligands for catalysis.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.

Basic Information

Product Name	5-Bromo-1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid
CAS No.	1222175-20-3
Molecular Formula	C8H5BrN2O2
Molecular Weight	241.04 g/mol
Synonyms	5-Bromo-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid; 5-Bromo-2-carboxy-1H-pyrrolo[2,3-b]pyridine; 5-Bromo-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid; 2-Carboxy-5-bromo-1H-pyrrolo[2,3-b]pyridine; 1222175-20-3; 5-Bromo-1H-7-azaindole-2-carboxylic acid; 5-Bromo-7-azaindole-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Bromo-1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support compliance with cGMP, ICH guidelines, and relevant pharmacopeial standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.