Description

7-Benzyl-4,7-Diazaspiro[2.5]Octane is a specialized spirocyclic amine building block of significant interest in advanced organic synthesis. Its unique constrained bicyclic structure, featuring a spiro-fused cyclopropane ring, makes it a valuable scaffold for constructing complex molecules with potential for high biological activity. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) targets and enzyme inhibitors.
• Medicinal Chemistry Scaffold: Used to explore structure-activity relationships (SAR) by introducing conformational constraints into lead compounds, potentially improving potency and selectivity.
• Ligand Synthesis: Serves as a precursor for creating sophisticated ligands in catalysis and for metal-organic frameworks (MOFs).
• Agrochemical Research: Employed in the development of new crop protection agents and pesticides due to its unique heterocyclic architecture.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein function.
• Academic Research: A valuable reagent for methodological studies in organic synthesis, particularly in spirocycle and strained ring system formation.

Basic Information

Product Name	7-Benzyl-4,7-Diazaspiro[2.5]Octane
CAS No.	1222106-45-7
Molecular Formula	C13H18N2
Molecular Weight	202.30 g/mol
Synonyms	7-Benzyl-4,7-diazaspiro[2.5]octane; 4,7-Diazaspiro[2.5]octane, 7-benzyl-; 1-Benzyl-4,7-diazaspiro[2.5]octane; 7-Benzyl-1,4-diazaspiro[2.5]octane; 7-Benzyl-4,7-diaza-spiro[2.5]octane; BDBO; 1222106-45-7
EINECS	Contact for details

Quality Control

Our 7-Benzyl-4,7-Diazaspiro[2.5]Octane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent identity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.