Description

tert-Butyl 2-Chloro-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate is a high-value, heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because it provides a versatile and protected scaffold for constructing complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Serves as a building block for developing new active ingredients in crop protection and pest management products.
• Chemical Biology Probe Synthesis: Used to create tool compounds for studying biological pathways and target validation in early-stage drug discovery.
• Library Synthesis for High-Throughput Screening: Enables the rapid generation of diverse compound libraries for screening against novel biological targets.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale production of complex molecules.
• Fine Chemical Synthesis: A versatile intermediate for synthesizing specialty chemicals, dyes, and advanced materials.

Basic Information

Product Name	tert-Butyl 2-Chloro-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate
CAS No.	1221931-40-3
Molecular Formula	C11H15ClN2O2S
Molecular Weight	274.77 g/mol
Synonyms	tert-Butyl 2-chloro-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-5-carboxylate; 5-tert-Butoxycarbonyl-2-chloro-6,7-dihydro-4H-thiazolo[5,4-c]pyridine; 2-Chloro-5-[(2-methylpropan-2-yl)oxycarbonyl]-6,7-dihydro-4H-thiazolo[5,4-c]pyridine; 2-Chloro-5-(tert-butoxycarbonyl)-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine; BOC-2-Chloro-DHTP; tert-Butyl 2-chloro-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridine-5-carboxylate
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Chloro-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.