Description

cis-tert-Butyl 3,5-Dimethyl-4-Oxopiperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a protected piperidone scaffold. This compound is of significant value for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting neurological and metabolic disorders. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical industries for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of novel drug candidates, especially in medicinal chemistry programs.
• API Synthesis: Serves as a crucial precursor for constructing the core piperidine/piperidone structures found in various therapeutic agents.
• Process Chemistry & R&D: Used in route scouting, optimization, and kilogram-scale production for clinical trial material.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development and quality control in API manufacturing.
• Custom Synthesis: A starting material for the custom manufacturing of specialized derivatives and analogs for biological screening.

Basic Information

Product Name	cis-tert-Butyl 3,5-Dimethyl-4-Oxopiperidine-1-Carboxylate
CAS No.	1221821-84-6
Molecular Formula	C12H21NO3
Molecular Weight	227.30 g/mol
Synonyms	1-Boc-3,5-dimethyl-4-piperidone; tert-Butyl 3,5-dimethyl-4-oxopiperidine-1-carboxylate; 4-Piperidinone, 3,5-dimethyl-1-[(1,1-dimethylethoxy)carbonyl]-; 1-N-Boc-3,5-dimethyl-4-piperidone; 3,5-Dimethyl-1-Boc-4-piperidone; 1-(tert-Butoxycarbonyl)-3,5-dimethyl-4-piperidone; cis-1-Boc-3,5-dimethylpiperidin-4-one
EINECS	Contact for details

Quality Control

Our cis-tert-Butyl 3,5-Dimethyl-4-Oxopiperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to ensure full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.