Description

3-(4-Chlorophenyl)-3-Oxetaneacetic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its unique oxetane ring structure. This compound is of significant commercial importance for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its versatile oxetane moiety.
• Agrochemical Synthesis: Serves as a precursor in the development of new generation pesticides and herbicides.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for specialized chemical entities.
• Academic Research: Utilized in universities and research institutes for methodological development and novel organic synthesis.
• Process Chemistry: Investigated for scalable route development and optimization for commercial API manufacturing.

Basic Information

Product Name	3-(4-Chlorophenyl)-3-Oxetaneacetic Acid Ethyl Ester
CAS No.	1221819-51-7
Molecular Formula	C13H15ClO3
Molecular Weight	254.71 g/mol
Synonyms	Ethyl 3-(4-chlorophenyl)-3-oxetaneacetate; 3-Oxetaneacetic acid, 3-(4-chlorophenyl)-, ethyl ester; 3-(p-Chlorophenyl)-3-oxetanylacetic acid ethyl ester; Oxetane-3-acetic acid, 3-(4-chlorophenyl)-, ethyl ester; 1221819-51-7; Ethyl [3-(4-chlorophenyl)oxetan-3-yl]acetate; 3-(4-Chlorophenyl)oxetane-3-acetic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 3-(4-Chlorophenyl)-3-Oxetaneacetic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.