Description

tert-Butyl 11-Oxo-5,10-Diazaspiro[5.5]Undecan-5-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic diaza scaffold. This compound is of significant value for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical companies and contract research organizations (CROs) engaged in the discovery of new therapeutic agents, particularly in areas requiring sophisticated heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• API Development: Employed in the process development and scale-up of new chemical entities (NCEs) requiring a spirocyclic diaza structure.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the cGMP production of clinical trial materials.
• Bioconjugation & Probe Synthesis: The reactive carbonyl and protected amine groups make it suitable for creating chemical probes or conjugates for biological testing.

Basic Information

Product Name	tert-Butyl 11-Oxo-5,10-Diazaspiro[5.5]Undecan-5-Carboxylate
CAS No.	1221818-91-2
Molecular Formula	C14H24N2O3
Molecular Weight	268.35 g/mol
Synonyms	5-[(1,1-Dimethylethoxy)carbonyl]-5,10-diazaspiro[5.5]undecan-11-one; tert-Butyl 11-oxo-5,10-diazaspiro[5.5]undecane-5-carboxylate; 5,10-Diazaspiro[5.5]undecan-11-one, 5-[(1,1-dimethylethoxy)carbonyl]-; 5-Boc-5,10-diazaspiro[5.5]undecan-11-one; Boc-Protected 5,10-Diazaspiro[5.5]undecan-11-one; 1221818-91-2
EINECS	Contact for details

Quality Control

Our tert-Butyl 11-Oxo-5,10-Diazaspiro[5.5]Undecan-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with the standards expected for pharmaceutical R&D and cGMP intermediate production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.