Description

2-Oxo-Octahydro-[1,6]Naphthyridine-6-Carboxylic Acid tert-Butyl Ester is a high-value, advanced pharmaceutical intermediate characterized by its complex fused bicyclic structure. This compound is critical for the synthesis of sophisticated active pharmaceutical ingredients (APIs), particularly in the development of protease inhibitors and other therapeutic agents. It is primarily sought by research institutions and manufacturers in the global pharmaceutical and biotechnology sectors for its role in constructing complex molecular architectures.

Application

• Key Intermediate in Pharmaceutical Synthesis: Serves as a crucial building block for the development of novel drug candidates, especially protease inhibitors.
• Research & Development (R&D): Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Manufacturing: Employed in the scaled-up production of Active Pharmaceutical Ingredients (APIs) requiring the 2-oxo-octahydro-[1,6]naphthyridine core.
• Contract Manufacturing Organizations (CMOs): Supplied to CMOs specializing in the custom synthesis of complex intermediates for client drug development pipelines.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	2-Oxo-Octahydro-[1,6]Naphthyridine-6-Carboxylic Acid tert-Butyl Ester
CAS No.	1221818-65-0
Molecular Formula	C13H20N2O3
Molecular Weight	252.31 g/mol
Synonyms	tert-Butyl 2-oxo-1,2,3,4,6,7,8,9-octahydro-[1,6]naphthyridine-6-carboxylate; 6-(tert-Butoxycarbonyl)-2-oxo-1,2,3,4,6,7,8,9-octahydro-[1,6]naphthyridine; 2-Oxo-1,2,3,4,6,7,8,9-octahydro-[1,6]naphthyridine-6-carboxylic acid 1,1-dimethylethyl ester; BOC-2-oxo-octahydro-[1,6]naphthyridine-6-carboxylate; (6-tert-Butoxycarbonyl-2-oxo-octahydro-[1,6]naphthyridine)
EINECS	Contact for details

Quality Control

Our 2-Oxo-Octahydro-[1,6]Naphthyridine-6-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.