Description

tert-Butyl Hexahydro-1,6-Naphthyridine-6(1H,2H,7H)-Carboxylate CAS NO 1221818-15-0 is a protected heterocyclic amine derivative, serving as a crucial advanced pharmaceutical intermediate in modern organic synthesis. Its primary value lies in its role as a versatile building block for constructing complex nitrogen-containing molecular scaffolds. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in medicinal chemistry programs targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its naphthyridine core structure.
• Organic Synthesis Reagent: Serves as a protected amine precursor in multi-step synthesis, enabling complex molecule construction for academic and industrial research.
• Ligand and Catalyst Development: Potential precursor for creating novel chiral ligands or organocatalysts used in asymmetric synthesis.
• Chemical Biology Probe Synthesis: Utilized in the creation of molecular probes for studying biological pathways and protein interactions.

Basic Information

Product Name	tert-Butyl Hexahydro-1,6-Naphthyridine-6(1H,2H,7H)-Carboxylate
CAS No.	1221818-15-0
Molecular Formula	C13H22N2O2
Molecular Weight	238.33 g/mol
Synonyms	tert-Butyl 1,2,3,4,7,8-hexahydro-1,6-naphthyridine-6-carboxylate; 6-Boc-1,2,3,4,7,8-hexahydro-1,6-naphthyridine; 1,6-Naphthyridine-6(1H,2H,7H)-carboxylic acid, 1,2,3,4,7,8-hexahydro-, 1,1-dimethylethyl ester; Boc-1,2,3,4,7,8-hexahydro-1,6-naphthyridine; tert-Butyl 1,2,3,4,7,8-hexahydro-1,6-naphthyridine-6(1H)-carboxylate
EINECS	Contact for details

Quality Control

Our tert-Butyl Hexahydro-1,6-Naphthyridine-6(1H,2H,7H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and MS, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.