Description

3-Chloro-5-Fluoropyridine 1-Oxide is a high-purity, halogenated pyridine derivative, a crucial building block in advanced organic synthesis. Its value lies in its unique reactivity as a functionalized heterocyclic scaffold, enabling the construction of complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infectives.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Custom Synthesis & Contract Manufacturing: A critical raw material for fine chemical manufacturers offering bespoke synthesis services.

Basic Information

Product Name	3-Chloro-5-Fluoropyridine 1-Oxide
CAS No.	1221793-68-5
Molecular Formula	C5H3ClFNO
Molecular Weight	147.54 g/mol
Synonyms	3-Chloro-5-fluoropyridine N-oxide; 5-Fluoro-3-chloropyridine 1-oxide; 3-Chloro-5-fluoropyridine oxide; Pyridine, 3-chloro-5-fluoro-, 1-oxide; 3-Chloro-5-fluoro-1-oxidopyridin-1-ium
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-Fluoropyridine 1-Oxide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.