Description

Diethyl 3-Cyano-6-Cyclopropyl-2,5-Pyridinedicarboxylate is a high-value, multi-functional pyridine derivative serving as a critical advanced intermediate in modern organic synthesis. Its molecular architecture, featuring both cyano and ester functional groups on a cyclopropyl-substituted pyridine core, makes it an essential building block for constructing complex heterocyclic systems. This compound is primarily utilized by research institutions and pharmaceutical development teams focused on creating novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and kinase inhibitors.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the biological activity of the pyridine and cyclopropane motifs.
• Ligand and Catalyst Synthesis: Serves as a starting material for creating sophisticated chelating ligands and organocatalysts used in asymmetric synthesis and transition metal catalysis.
• Material Science Precursor: Employed in the research and development of organic electronic materials, such as non-linear optical (NLO) chromophores and charge-transport molecules.
• Chemical Biology Probe Development: Utilized to build molecular probes and tags for studying enzyme function and cellular processes.

Basic Information

Product Name	Diethyl 3-Cyano-6-Cyclopropyl-2,5-Pyridinedicarboxylate
CAS No.	1221792-74-0
Molecular Formula	C14H16N2O4
Molecular Weight	276.29 g/mol
Synonyms	3-Cyano-6-cyclopropyl-2,5-pyridinedicarboxylic acid diethyl ester; Diethyl 3-cyano-6-cyclopropylpyridine-2,5-dicarboxylate; 2,5-Pyridinedicarboxylic acid, 3-cyano-6-cyclopropyl-, diethyl ester; 6-Cyclopropyl-3-cyano-2,5-pyridinedicarboxylic Acid Diethyl Ester; 1221792-74-0; Diethyl 3-cyano-6-cyclopropyl-2,5-pyridinedicarboxylate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with stringent industry standards for research and development chemicals. We provide comprehensive analytical data including HPLC purity, identity confirmation via spectroscopic methods (NMR, IR, MS), and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications and test results are available for every batch upon request, supporting your regulatory and quality assurance documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.