Description

3,4-Dihydro-1H-Spiro[Naphthalene-2,2'-[1,3]Thiazolidine] Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its unique spiro-fused heterocyclic structure. This compound is critical for enabling complex synthetic pathways in modern drug discovery and development. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the synthesis of novel therapeutic agents, particularly within central nervous system (CNS) and oncology research.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting neurological pathways.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing novel spirocyclic and fused-ring heterocyclic compounds.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization programs.
• Pre-clinical Development: Employed in the production of compounds for pharmacological screening and toxicology studies.
• Chemical Reference Standard: Suitable for use as an analytical standard in method development and quality control laboratories.

Basic Information

Product Name	3,4-Dihydro-1H-Spiro[Naphthalene-2,2'-[1,3]Thiazolidine] Hydrochloride
CAS No.	1221792-02-4
Molecular Formula	C13H16ClNS
Molecular Weight	253.79 g/mol
Synonyms	1H-Spiro[Naphthalene-2,2'-[1,3]Thiazolidine], 3,4-Dihydro-, Hydrochloride; 3,4-Dihydro-1H-spiro[naphthalene-2,2'-thiazolidine] Hydrochloride; Spiro[naphthalene-2,2'-thiazolidine] Hydrochloride Derivative; 1,3-Thiazolidine, 3,4-dihydro-1H-spiro[naphthalene-2,2']-, Hydrochloride; 1221792-02-4; 3,4-Dihydrospiro[naphthalene-2,2'-thiazolidine] HCl
EINECS	Contact for details

Quality Control

Our 3,4-Dihydro-1H-Spiro[Naphthalene-2,2'-[1,3]Thiazolidine] Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.