Description

8-Cyclohexyl-1-thia-4,8-diazaspiro[4.5]decane hydrochloride is a high-purity, advanced pharmaceutical intermediate belonging to the spirocyclic amine class. This compound is valued for its unique structural framework, which is critical in the development of novel bioactive molecules targeting central nervous system and other therapeutic areas. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of new chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its spirocyclic scaffold.
• Chemical Biology: Serves as a probe or ligand in the study of biological targets and receptor interactions.
• Process Chemistry: Employed in route scouting and scale-up synthesis for active pharmaceutical ingredient (API) development.
• Reference Standard: Used as an analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	8-Cyclohexyl-1-thia-4,8-diazaspiro[4.5]decane hydrochloride
CAS No.	1221791-74-7
Molecular Formula	C13H25ClN2S
Molecular Weight	276.87 g/mol
Synonyms	8-Cyclohexyl-1-thia-4,8-diazaspiro[4.5]decane HCl; 1-Thia-4,8-diazaspiro[4.5]decane, 8-cyclohexyl-, hydrochloride; 8-Cyclohexyl-1-thia-4,8-diazaspiro[4.5]decanium chloride; Spiro[4.5]decane-8-cyclohexyl-1-thia-4,8-diazane hydrochloride
EINECS	Contact for details

Quality Control

Our 8-Cyclohexyl-1-thia-4,8-diazaspiro[4.5]decane hydrochloride is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.