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7-Bromo-3-Iodo-1H-Pyrrolo[3,2-C]Pyridine CAS NO 1221278-74-5


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CAS No.:1221278-74-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

7-Bromo-3-Iodo-1H-Pyrrolo[3,2-C]Pyridine is a high-value, multi-halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both bromo and iodo substituents on the fused pyrrolopyridine core, makes it a versatile intermediate for selective cross-coupling reactions and functional group transformations. This compound is primarily utilized by research scientists and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

  • Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates, particularly for kinase inhibitors and other targeted therapies.
  • Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its reactive halogen sites for derivatization.
  • Material Science: Acts as a building block for creating organic electronic materials, such as ligands for OLEDs or conductive polymers.
  • Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for biological target validation.
  • Cross-Coupling Reactions: The bromo and iodo groups offer orthogonal reactivity for sequential Suzuki, Sonogashira, Buchwald-Hartwig, and other palladium-catalyzed couplings.
  • Library Synthesis: A valuable scaffold for generating diverse compound libraries in medicinal chemistry for high-throughput screening.

Basic Information

Product Name 7-Bromo-3-Iodo-1H-Pyrrolo[3,2-C]Pyridine
CAS No. 1221278-74-5
Molecular Formula C7H4BrIN2
Molecular Weight 322.93 g/mol
Synonyms 7-Bromo-3-iodo-1H-pyrrolo[3,2-c]pyridine; 1H-Pyrrolo[3,2-c]pyridine, 7-bromo-3-iodo-; 3-Iodo-7-bromo-1H-pyrrolo[3,2-c]pyridine; 7-Bromo-3-iodopyrrolo[3,2-c]pyridine; Pyrrolo[3,2-c]pyridine, 7-bromo-3-iodo-1H-
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Quality Control

Our 7-Bromo-3-Iodo-1H-Pyrrolo[3,2-C]Pyridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, meeting the stringent requirements of research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and compliance needs in critical development phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to minimize exposure to moisture and atmospheric contaminants.

Specification

Item Specification
Appearance Off-white to light yellow crystalline powder
Identification (HPLC/MS) Conforms
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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