Description

2-Bromo-5-(Difluoromethyl)Pyridine, 97% is a high-purity, multi-functional halogenated pyridine derivative. This compound serves as a versatile and critical building block in advanced organic synthesis, particularly for introducing the difluoromethylpyridine moiety into complex molecular architectures. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for drug discovery and specialty chemical development.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and pesticides, leveraging the biological activity of the difluoromethyl group.
• Material Science Research: Serves as a precursor for creating functionalized ligands, organic electronic materials, and liquid crystals.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi cross-coupling reactions to form biaryl systems.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and library synthesis for lead optimization.
• Chemical Biology: Used as a probe or tag in the development of biochemical tools and diagnostic agents.

Basic Information

Product Name	2-Bromo-5-(Difluoromethyl)Pyridine, 97%
CAS No.	1221272-81-6
Molecular Formula	C6H4BrF2N
Molecular Weight	207.99 g/mol
Synonyms	2-Bromo-5-(difluoromethyl)pyridine; 5-(Difluoromethyl)-2-bromopyridine; 2-Bromo-5-difluoromethylpyridine; Pyridine, 2-bromo-5-(difluoromethyl)-; 1221272-81-6
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-(Difluoromethyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, GC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, ensuring full traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly closed and stored in a desiccator if long-term storage is required.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.