Description

8-Bromo-6-Methoxy-1,2,3,4-Tetrahydroisoquinoline is a high-purity, functionalized tetrahydroisoquinoline derivative that serves as a critical building block in advanced organic synthesis. This compound matters because it provides a versatile scaffold for constructing complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active compounds and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, cardiovascular diseases, and oncology.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Serves as a building block for creating novel active ingredients in crop protection and pest management products.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals and advanced materials.
• Academic Research: Utilized in universities and research institutes for methodological development and exploring new chemical transformations.
• Contract Research and Manufacturing (CRO/CMO): A valuable starting material for custom synthesis and scale-up projects under GMP or non-GMP conditions.

Basic Information

Product Name	8-Bromo-6-Methoxy-1,2,3,4-Tetrahydroisoquinoline
CAS No.	1220694-87-0
Molecular Formula	C₁₀H₁₂BrNO
Molecular Weight	242.11 g/mol
Synonyms	8-Bromo-6-methoxy-1,2,3,4-tetrahydroisoquinoline; 6-Methoxy-8-bromo-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-8-bromo-6-methoxyisoquinoline; 8-Bromo-6-methoxy-THIQ; 1220694-87-0; 8-Br-6-MeO-THIQ
EINECS	Contact for details

Quality Control

Our 8-Bromo-6-Methoxy-1,2,3,4-Tetrahydroisoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality commitment supports applications in regulated environments, and custom purity grades (e.g., >97%, >98%, >99%) are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This material is light-sensitive (store away from light). Keep the container sealed to protect from moisture and atmospheric contamination. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.