Description

(2-Chloropyridin-3-Yl)Methanamine Hydrochloride is a high-purity, versatile pharmaceutical intermediate and organic building block. Its value lies in its functionalized pyridine core, which serves as a critical scaffold for constructing complex molecules in medicinal chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries engaged in the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors, antiviral agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, leveraging the bioactivity of the chloropyridine moiety.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Employed in the design of molecular probes and affinity tags for studying biological systems and drug-target interactions.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Academic & Industrial R&D: Used in research laboratories for method development and exploring new chemical entities across various therapeutic areas.

Basic Information

Product Name	(2-Chloropyridin-3-Yl)Methanamine Hydrochloride
CAS No.	1220039-41-7
Molecular Formula	C6H8Cl2N2
Molecular Weight	179.05 g/mol
Synonyms	1-(2-Chloropyridin-3-yl)methanamine hydrochloride; (2-Chloro-3-pyridinyl)methanamine hydrochloride; 3-(Aminomethyl)-2-chloropyridine hydrochloride; 2-Chloro-3-(aminomethyl)pyridine hydrochloride; 2-Chloro-3-pyridinemethanamine hydrochloride; 2-Chloro-3-(aminomethyl)pyridine HCl; 1-(2-Chloro-3-pyridyl)methanamine hydrochloride
EINECS	Contact for details

Quality Control

Our (2-Chloropyridin-3-Yl)Methanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP standards where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.