Description

1-(5-Bromo-2-Pyridinyl)-3-Methylpiperidine CAS NO 1220038-72-1 is a high-purity, advanced pharmaceutical intermediate featuring a brominated pyridine core linked to a methyl-substituted piperidine ring. This specific molecular architecture makes it a critical building block for medicinal chemists developing novel active pharmaceutical ingredients (APIs), particularly in the areas of central nervous system (CNS) and oncology research. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex drug candidates.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug candidates, particularly for CNS disorders and oncology.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its versatile bromine handle for further functionalization.
• Ligand Synthesis: Serves as a building block for creating complex ligands used in catalysis or as pharmacophores in drug design.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development and quality control in API manufacturing.
• Academic & Industrial R&D: Utilized in exploratory organic synthesis for developing new heterocyclic compounds with potential biological activity.

Basic Information

Product Name	1-(5-Bromo-2-Pyridinyl)-3-Methylpiperidine
CAS No.	1220038-72-1
Molecular Formula	C11H15BrN2
Molecular Weight	255.16 g/mol
Synonyms	3-Methyl-1-(5-bromopyridin-2-yl)piperidine; 1-(5-Bromo-2-pyridyl)-3-methylpiperidine; 5-Bromo-2-(3-methylpiperidin-1-yl)pyridine; 2-(3-Methyl-1-piperidinyl)-5-bromopyridine
EINECS	Contact for details

Quality Control

Our 1-(5-Bromo-2-Pyridinyl)-3-Methylpiperidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.