Description

Azetidin-3-Yl 2-Phenylacetate is a high-value, specialized organic compound featuring a unique azetidine ring system esterified with a phenylacetic acid moiety. This structural motif makes it a critical advanced pharmaceutical intermediate (API) and a versatile building block for medicinal chemistry research. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams for developing novel therapeutic agents, particularly in the areas of β-lactam antibiotics and central nervous system (CNS) modulators.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel β-lactam antibiotics and other nitrogen-containing heterocyclic drugs.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Protease Inhibitor Development: Used in the research and development of enzyme inhibitors targeting various disease pathways.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Custom Synthesis Building Block: Provides a critical chiral or functionalized component for contract research organizations (CROs) and CDMOs performing custom synthesis.
• Academic Research: Utilized in university and institutional labs for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	Azetidin-3-Yl 2-Phenylacetate
CAS No.	1220037-63-7
Molecular Formula	C11H13NO2
Molecular Weight	191.23 g/mol
Synonyms	3-Azetidinyl phenylacetate; Azetidin-3-ol, 2-phenylacetate; 2-Phenylacetic acid azetidin-3-yl ester; 3-Hydroxyazetidine phenylacetate; 1-Azabicyclo[1.2.0]butan-3-yl 2-phenylacetate; Phenylacetic acid azetidin-3-yl ester; (Azetidin-3-yloxy)carbonylmethylbenzene
EINECS	Contact for details

Quality Control

Our Azetidin-3-Yl 2-Phenylacetate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting purity, impurity profile, and other critical parameters to support your regulatory and R&D documentation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.