Description

n-(2-Hydroxyethyl)-4,5,6,7-Tetrahydro-1H-Pyrazolo-[4,3-C]Pyridine-3-Carboxamide Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1220035-11-9. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder research. It is essential for pharmaceutical R&D laboratories and manufacturers seeking reliable, high-quality raw materials for process development and scale-up.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel therapeutic agents, particularly for neurological and psychiatric applications.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core scaffold in the research and production of new drug candidates targeting specific receptors.
• Biochemical Research: Used in academic and industrial laboratories for pharmacological studies and mechanism of action investigations.
• Process Chemistry & Scale-Up: Employed in optimizing synthetic routes and scaling production from laboratory to pilot and commercial scale.
• Reference Standard: Utilized as an analytical standard for quality control and method validation in pharmaceutical manufacturing.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	n-(2-Hydroxyethyl)-4,5,6,7-Tetrahydro-1H-Pyrazolo-[4,3-C]Pyridine-3-Carboxamide Hydrochloride
CAS No.	1220035-11-9
Molecular Formula	C11H17ClN4O2
Molecular Weight	272.73 g/mol
Synonyms	1H-Pyrazolo[4,3-c]pyridine-3-carboxamide, N-(2-hydroxyethyl)-4,5,6,7-tetrahydro-, hydrochloride (1:1); 4,5,6,7-Tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carboxamide, N-(2-hydroxyethyl)-, monohydrochloride; 1220035-11-9; N-(2-Hydroxyethyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carboxamide HCl; UNII-7K8I6WQ8KJ; 7K8I6WQ8KJ; CHEMBL3185992
EINECS	Contact for details

Quality Control

Our n-(2-Hydroxyethyl)-4,5,6,7-Tetrahydro-1H-Pyrazolo-[4,3-C]Pyridine-3-Carboxamide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.