Description

(3-Methyl-1-Piperidinyl)(4,5,6,7-Tetrahydro-1H-Pyrazolo[4,3-C]Pyridin-3-Yl)Methanone Hcl is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1220035-03-9. This compound is a key building block in modern medicinal chemistry, valued for its complex heterocyclic structure which is integral to the synthesis of potent and selective bioactive molecules. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly within the central nervous system (CNS) and oncology research fields.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, especially those targeting specific receptor subtypes.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new chemical entities.
• CNS Drug Development: Serves as a core scaffold for compounds being investigated for neurological and psychiatric disorders.
• Oncology Research: Employed in the synthesis of potential kinase inhibitors and other targeted cancer therapies.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and pharmacological studies.

Basic Information

Item	Detail
Product Name	(3-Methyl-1-Piperidinyl)(4,5,6,7-Tetrahydro-1H-Pyrazolo[4,3-C]Pyridin-3-Yl)Methanone Hydrochloride
CAS No.	1220035-03-9
Molecular Formula	C16H22N4O • HCl
Molecular Weight	322.84 g/mol (Free base: 286.37 g/mol)
Synonyms	3-[(3-Methyl-1-piperidinyl)carbonyl]-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine hydrochloride; (3-Methylpiperidin-1-yl)(4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl)methanone hydrochloride; 1H-Pyrazolo[4,3-c]pyridine, 4,5,6,7-tetrahydro-3-[(3-methyl-1-piperidinyl)carbonyl]-, hydrochloride; CAS 1220035-03-9
EINECS	Contact for details

Quality Control

Our (3-Methyl-1-Piperidinyl)(4,5,6,7-Tetrahydro-1H-Pyrazolo[4,3-C]Pyridin-3-Yl)Methanone Hcl is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.