Description

3-Pyrrolidinylmethyl 4-Chloro-2-Pyridinecarboxylate Hydrochloride is a high-purity, advanced pharmaceutical intermediate crucial for modern drug discovery and development. This compound serves as a key building block in the synthesis of complex molecules, particularly for targeting neurological and metabolic pathways. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs) and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, especially in central nervous system (CNS) and metabolic disorder research.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Synthesis: Employed in the production route for potential APIs targeting specific receptors or enzymes.
• Biochemical Tool Compound: Serves as a reference standard or a probe molecule in pharmacological and biochemical assays.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs and CROs for custom synthesis and process development projects.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and pharmacological studies.

Basic Information

Product Name	3-Pyrrolidinylmethyl 4-Chloro-2-Pyridinecarboxylate Hydrochloride
CAS No.	1220031-41-3
Molecular Formula	C12H15ClN2O2·HCl
Molecular Weight	291.18 g/mol
Synonyms	4-Chloro-2-pyridinecarboxylic acid 3-pyrrolidinylmethyl ester hydrochloride; 3-((4-Chloropicolinoyloxy)methyl)pyrrolidine hydrochloride; 1-(4-Chloro-2-pyridinylcarbonyloxy)-3-pyrrolidinepropanol hydrochloride (obsolete); PYR-4Cl-COOH-OMe.HCl (abbrev.); (4-Chloro-pyridin-2-yl)-[3-(pyrrolidin-1-ylmethyl)-propyl] ester hydrochloride; 4-Chloro-picolinic acid 3-pyrrolidin-1-ylmethyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Pyrrolidinylmethyl 4-Chloro-2-Pyridinecarboxylate Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We adhere to cGMP guidelines where applicable, and all materials are supported by comprehensive analytical data. A Certificate of Analysis (COA) detailing identity, purity (HPLC), and impurity profiles is provided with each shipment to ensure full traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.