Description

3-Azetidinyl 2-Chloroacetate is a specialized organic building block featuring a reactive azetidine ring and a chloroacetate ester group. This compound is of significant value in advanced organic synthesis, particularly for the construction of complex nitrogen-containing heterocycles and pharmacologically active molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel β-lactam analogs, azetidine-based drug candidates, and other bioactive molecules targeting neurological and metabolic disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage the azetidine moiety for enhanced biological activity.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and transition metal catalysis.
• Polymer Modification: Employed to introduce functional azetidine groups into polymer backbones, modifying material properties for specialty coatings or adhesives.
• Chemical Biology Probe Development: Utilized in the design of molecular probes and activity-based protein profiling (ABPP) agents to study enzyme function.

Basic Information

Product Name	3-Azetidinyl 2-Chloroacetate
CAS No.	1220020-50-7
Molecular Formula	C5H8ClNO2
Molecular Weight	149.57 g/mol
Synonyms	2-Chloroacetic Acid Azetidin-3-yl Ester; Azetidin-3-yl 2-Chloroacetate; 3-Azetidinol, 2-Chloroacetate; 3-Hydroxyazetidine 2-Chloroacetate; Azetidine-3-yl Chloroacetate; 3-Chloroacetoxyazetidine; (Azetidin-3-yloxy)carbonylmethyl Chloride
EINECS	Contact for details

Quality Control

Every batch of 3-Azetidinyl 2-Chloroacetate is manufactured and tested under strict quality management protocols to ensure high purity and consistency. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as oxidizing agents. Due to its light-sensitive nature and reactivity, it is recommended to handle under an inert atmosphere for extended storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.