Description

3-Azetidinyl 4-Chloro-2-Pyridinecarboxylate is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1219979-63-1. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting neurological and inflammatory pathways. It is primarily utilized by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in novel drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic entities.
• Process Chemistry Development: Serves as a standard or starting material for scaling up API synthesis under cGMP conditions.
• Academic Research: Employed in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.
• Bioconjugation & Probe Development: Potential use in creating chemical probes or tagged molecules for biological assay development.

Basic Information

Product Name	3-Azetidinyl 4-Chloro-2-Pyridinecarboxylate
CAS No.	1219979-63-1
Molecular Formula	C9H9ClN2O2
Molecular Weight	212.63 g/mol
Synonyms	4-Chloro-2-pyridinecarboxylic acid azetidin-3-yl ester; 3-Azetidinyl 4-chloropicolinate; Azetidin-3-yl 4-chloropyridine-2-carboxylate; 4-Chloro-2-(azetidin-3-yloxycarbonyl)pyridine; 1219979-63-1; 4-Chloro-picolinic acid azetidin-3-yl ester; 3-Azetidinyl ester of 4-chloropicolinic acid
EINECS	Contact for details

Quality Control

Our 3-Azetidinyl 4-Chloro-2-Pyridinecarboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent control of residual solvents and impurities. We provide full traceability and Certificates of Analysis (COA) are supplied with every shipment to ensure compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.