Description

2-[2-(2-Piperidinyl)Ethoxy]-5-(Trifluoromethyl)-Pyridine Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its specific piperidine and trifluoromethyl pyridine structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical companies and contract research organizations (CROs) engaged in developing central nervous system (CNS) and other therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• CNS Drug Development: Particularly relevant for the research of compounds interacting with neurological receptors due to its piperidine moiety.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a precursor in multi-step synthetic routes for final API manufacturing.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing research and scale-up services to the pharmaceutical industry.
• Preclinical & Clinical Trial Material Production: Used to produce batches of investigational compounds for non-clinical and clinical studies.

Basic Information

Product Name	2-[2-(2-Piperidinyl)Ethoxy]-5-(Trifluoromethyl)-Pyridine Hydrochloride
CAS No.	1219976-75-6
Molecular Formula	C13H17F3N2O • HCl
Molecular Weight	310.75 g/mol
Synonyms	5-(Trifluoromethyl)-2-[2-(2-piperidinyl)ethoxy]pyridine hydrochloride; 2-[2-(Piperidin-2-yl)ethoxy]-5-(trifluoromethyl)pyridine HCl; 2-(2-(2-Piperidinyl)ethoxy)-5-(trifluoromethyl)pyridine hydrochloride; 2-Piperidineethanol, 5-(trifluoromethyl)-2-pyridinyl ether, hydrochloride; 1219976-75-6; UNII-9V8I2W8T4F; 9V8I2W8T4F
EINECS	Contact for details

Quality Control

Our 2-[2-(2-Piperidinyl)Ethoxy]-5-(Trifluoromethyl)-Pyridine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) documenting all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.