Description

2-{2-[(2-Fluorobenzyl)Oxy]Ethyl}Piperidinehydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its specific piperidine and fluorobenzyl ether structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and receptor-targeted therapeutics. It is primarily needed by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates, especially those targeting neurological pathways.
• Drug Discovery & Medicinal Chemistry: Used in research and development for structure-activity relationship (SAR) studies and lead optimization.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a key chiral building block for constructing the core scaffold of potential APIs.
• Biochemical Research: Employed as a reagent or ligand in biochemical assays and pharmacological studies.
• Process Development & Scale-up: Utilized in optimizing synthetic routes from laboratory scale to pilot and commercial production.

Basic Information

Product Name	2-{2-[(2-Fluorobenzyl)Oxy]Ethyl}Piperidinehydrochloride
CAS No.	1219967-69-7
Molecular Formula	C14H20FNO•HCl
Molecular Weight	273.78 g/mol (Free base: 237.31 g/mol)
Synonyms	2-(2-((2-Fluorobenzyl)oxy)ethyl)piperidine hydrochloride; 2-[2-[(2-Fluorophenyl)methoxy]ethyl]piperidine HCl; 1-(2-((2-Fluorobenzyl)oxy)ethyl)piperidine hydrochloride; Piperidine, 2-[2-[(2-fluorophenyl)methoxy]ethyl]-, hydrochloride; 2-Fluorobenzyl 2-piperidinoethyl ether hydrochloride
EINECS	Contact for details

Quality Control

Our 2-{2-[(2-Fluorobenzyl)Oxy]Ethyl}Piperidinehydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D and cGMP starting material applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.